ADRB2抗体;ADRB2 Polyclonal Antib

Description This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. References 1.World J Gastroenterol. 2015 Jun 21;21(23):7191-6. 2.Adv Exp Med Biol. 2015;842:247-61. Specification Aliases:BAR; B2AR; ADRBR; ADRB2R; BETA2AR Entrez GeneID:154 Swissprot:P07550 clone:5G3B5 WB Predicted band size:46.5kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Rat Immunogen:Purified recombinant fragment of human ADRB2 (AA: 302-413) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 FCM:1/200 - 1/400 ELISA:1/10000