VAMP2抗体;VAMP2 Polyclonal Antib

Description The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. References Alzheimers Res Ther. 2021 Jun 28;13(1):119.Cell Mol Immunol. 2018 Apr;15(4):353-366. Specification Aliases:SYB2; VAMP-2; NEDHAHM Entrez GeneID:6844 Swissprot:P63027 clone:5A2C7 WB Predicted band size:12.7kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse, Monkey, Rat Immunogen:Purified recombinant fragment of human VAMP2 (AA: 2-89aa) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000