PGLYRP1抗体;PGLYRP1 Polyclonal A

Description Peptidoglycan recognition proteins (PGRPs) are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-Iå and PGRP-I∫ are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors. Specification Aliases:PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L Swissprot:O75594 WB Predicted band size:22 kDa Host/Isotype:Rabbit IgG Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse, Rat Immunogen:Synthetic peptide of human PGLYRP1 Formulation:pH7.4 PBS, 0.05% NaN3, 40% Glycerol Application WB:1/200-1/1000 ELISA:1/1000-1/2000