SLC22A12抗体;SLC22A12 Polyclonal

Description The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. References 1.Rheumatology (Oxford). 2020 Dec 1;59(12):3988-3990.2.PLoS One. 2020 Apr 9;15(4):e0231336. Specification Aliases:RST; OAT4L; URAT1 Entrez GeneID:116085 Swissprot:Q96S37 clone:1B1G7 WB Predicted band size:59.6kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse Immunogen:Purified recombinant fragment of human SLC22A12 (AA: 30-145) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000