NEFH抗体;NEFH Polyclonal Antibod

Description Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. References 1.J Neurol Sci. 2011 May 15;304(1-2):117-21. 2.Neurochem Res. 2011 Dec;36(12):2287-91. Specification Aliases:NFH Entrez GeneID:4744 Swissprot:P12036 clone:8H10 WB Predicted band size:112.4kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 ELISA:1/10000