CYP46A1抗体;CYP46A1 Polyclonal A

Description This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. Specification Aliases:CP46; CYP46 Swissprot:Q9Y6A2 Host/Isotype:Rabbit IgG Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse Immunogen:Synthetic peptide of human CYP46A1 Formulation:pH7.4 PBS, 0.05% NaN3, 40% Glycerol Application IHC:1/25-1/100 ELISA:1/1000-1/2000