CRKL抗体;CRKL Polyclonal Antibod

Description This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. References 1. Mol Cell Biol. 2009 Jun;29(11):3076-87. 2. Cell. 2009 Jul 23;138(2):389-403. Specification Aliases:CRKL Entrez GeneID:1399 Swissprot:P46109 clone:5E12 WB Predicted band size:39kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human CRKL expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application FCM:1/200 - 1/400 ELISA:1/10000