PAK3抗体;PAK3 Polyclonal Antibod

Description The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. References 1.J Mol Biol. 2014 Oct 23;426(21):3520-38. 2.J Biol Chem. 2011 Nov 18;286(46):40044-59. Specification Aliases:ARA; bPAK; MRX30; MRX47; OPHN3; PAK-3; PAK3beta; beta-PAK Entrez GeneID:5063 Swissprot:O75914 clone:4G8F11 WB Predicted band size:62.3kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Monkey Immunogen:Purified recombinant fragment of human PAK3 (AA: 1-100) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 ELISA:1/10000