MUC2抗体;MUC2 Polyclonal Antibod

Description This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. References 1.Hum Pathol. 2014 Mar;45(3):540-8. 2.PLoS One. 2013 Dec 6;8(12):e79769. Specification Aliases:MLP; SMUC; MUC-2 Entrez GeneID:4583 Swissprot:Q02817 clone:2G4B7 WB Predicted band size:540kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human MUC2 (AA: 4373-4557) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application FCM:1/200 - 1/400 ELISA:1/10000