CD163抗体;CD163 Polyclonal Antib

Description The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. References 1.J Cancer Res Clin Oncol. 2018 Jul;144(7):1253-1263. 2.Cancer Biomark. 2018 Feb 14;21(3):689-700. Specification Aliases:M130; MM130; SCARI1 Entrez GeneID:9332 Swissprot:Q86VB7 clone:7G5E2 WB Predicted band size:125.4kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse Immunogen:Purified recombinant fragment of human CD163 (AA: extra 42-259) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000