YWHAQ抗体;YWHAQ Polyclonal Antib

Description This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008] References 1.PLoS Genet. 2016 Mar 23;12(3):e1005919. 2.Biochem Biophys Res Commun. 2010 Nov 19;402(3):543-8. Specification Aliases:1C5; HS1; 14-3-3 Entrez GeneID:10971 Swissprot:P27348 clone:5C4E7 WB Predicted band size:27.8kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Mouse,Rat,Monkey Immunogen:Purified recombinant fragment of human YWHAQ (AA: 1-245) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 ELISA:1/10000