SSTR3抗体;SSTR3 Polyclonal Antib

Description This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. References 1. J Gastroenterol Hepatol. 2008 Mar;23(3):424-9. 2. Cancer Biol Ther. 2004 Aug;3(8):726-30. Specification Aliases:SS3R; SS3-R; SS-3-R; SSR-28 Entrez GeneID:6753 Swissprot:P32745 clone:7H8E5 WB Predicted band size:45.8kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Rat Immunogen:Purified recombinant fragment of human SSTR3 (AA: 1-43) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide. Application WB:1/500 - 1/2000 FCM:1/200 - 1/400 ELISA:1/10000