CEBPA抗体;CEBPA Polyclonal Antib

Description The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. References Haematologica. 2009 Aug;94(8):1075-84. Br J Cancer. 2009 Aug 18;101(4):738-40. Specification Aliases:CEBP; C/EBP-alpha Entrez GeneID:1050 Swissprot:P49715 clone:4E10 WB Predicted band size:37.5kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human CEBPA expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 FCM:1/200 - 1/400 ELISA:1/10000