CBX1抗体;CBX1 Polyclonal Antibod

Description This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. References 1. Cell. 2003 Nov 26;115(5):523-35. 2. Cell. 2005 Sep 23;122(6):957-68. 3. Cell. 2006 Nov 3;127(3):635-48. Specification Aliases:CBX; M31; MOD1; p25beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta; CBX1 Entrez GeneID:10951 Swissprot:P83916 clone:5A3 WB Predicted band size:21kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Monkey Immunogen:Purified recombinant fragment of human CBX1 expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application WB:1/500 - 1/2000 ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000