PIK3R1抗体;PIK3R1 Polyclonal Ant

Description Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. References 1.Cancer Epidemiol Biomarkers Prev. 2011 May;20(5):923-33. 2.Cancer Res. 2010 Jul 1;70(13):5305-15. Specification Aliases:p85; GRB1; p85-ALPHA Entrez GeneID:5295 Swissprot:P27986 clone:6G10 WB Predicted band size:83.6kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Mouse Immunogen:Purified recombinant fragment of human PIK3R1 (AA: 159-388) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 ICC:1/100 FCM:1/200 - 1/400 ELISA:1/10000