HDAC1抗体;HDAC1 Polyclonal Antib

Description Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. References 1.Cell Commun Signal. 2019 Jul 29;17(1):86. 2.Hum Pathol. 2019 Mar;85:194-201. Specification Aliases:HD1; RPD3; KDAC1; GON-10; RPD3L1 Entrez GeneID:3065 Swissprot:Q13547 clone:1B6A7 WB Predicted band size:55.1kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse, Rat Immunogen:Purified recombinant fragment of human HDAC1 (AA: 321-482) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000