CD14抗体;CD14 Polyclonal Antibod

Description CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages. References 1. J Mammary Gland Biol Neoplasia 2000, 5 : 227-241.2. J Mammary Gland Biol Neoplasia 2000, 5 : 165-185. Specification Aliases:CD14 Entrez GeneID:929 Swissprot:P08571 clone:5A3 Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human CD14 expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application IHC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000