SDHA抗体;SDHA Polyclonal Antibod

Description This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. References 1,Cancer Sci . 2021 Aug;112(8):3375-3387. 2,Medicine (Baltimore) . 2020 Oct 9;99(41):e22497. Specification Aliases:FP; PGL5; SDH1; SDH2; SDHF; CMD1GG; MC2DN1; NDAXOA Entrez GeneID:6389 Swissprot:P31040 clone:2A10F6 WB Predicted band size:72.7KDa Host/Isotype:Mouse IgG2a Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse Immunogen:Purified recombinant fragment of human SDHA (AA: 516-665) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000