PTGS2抗体;PTGS2 Polyclonal Antib

Description Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. References 1,PLoS One. 2020 Sep 30;15(9):e0239856.2,Acta Gastroenterol Belg. Apr-Jun 2020;83(2):249-254. Specification Aliases:COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS Entrez GeneID:5743 Swissprot:P35354 clone:4C1H7 WB Predicted band size:69kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human PTGS2 (AA: 18-207) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000