EZR抗体;EZR Polyclonal Antibody

Description The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. References BMC Cancer. 2013 Nov 4;13:520. Cell Oncol (Dordr). 2013 Dec;36(6):485-91. Specification Aliases:CVL; CVIL; VIL2; HEL-S-105 Entrez GeneID:7430 Swissprot:P15311 clone:6F1C3 WB Predicted band size:69.4kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human EZR (AA: 292-464) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000