CCDC106抗体;CCDC106 Polyclonal A

Description The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53. Specification Aliases:ZNF581; HSU79303 Swissprot:Q9BWC9 Host/Isotype:Rabbit IgG Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse Immunogen:Fusion protein of human CCDC106 Formulation:pH7.4 PBS, 0.05% NaN3, 40% Glycerol Application IHC:1/100-1/300 ELISA:1/2000-1/10000