SOD2抗体;SOD2 Polyclonal Antibod

Description This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. References 1.Dis Markers. 2015;2015:746329. 2.Free Radic Biol Med. 2015 Dec;89:379-86. Specification Aliases:IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD Entrez GeneID:6648 Swissprot:P04179 clone:8H3D2 WB Predicted band size:24.7kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human SOD2 (AA: 1-222) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 ICC:1/50 - 1/250 FCM:1/200 - 1/400 ELISA:1/10000