SOD1抗体;SOD1 Polyclonal Antibod

Description SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene. References 1. Apoptosis. 2005 May;10(3):499-502. 2. Hum Mol Genet. 2008 Nov 1;17(21):3303-17. Specification Aliases:ALS; SOD; ALS1; IPOA; homodimer Entrez GeneID:6647 Swissprot:P00441 clone:6F5 WB Predicted band size:18kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Mouse Immunogen:Purified recombinant fragment of human SOD1 expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application WB:1/500 - 1/2000 ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000