SIRT6抗体;SIRT6 Polyclonal Antib

Description This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants. References 1.Mol Med Rep. 2014 Mar;9(3):882-8. 2.Carcinogenesis. 2013 Jul;34(7):1476-86. Specification Aliases:SIR2L6 Entrez GeneID:51548 Swissprot:Q8N6T7 clone:2G1H1 WB Predicted band size:39kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human SIRT6 (AA: 141-250) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000