PARK7抗体;PARK7 Polyclonal Antib

Description The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. References 1.Biochemistry (Mosc). 2021 Jun;86(6):627-640. 2.Sci Rep. 2021 Jul 16;11(1):14582. Specification Aliases:DJ1; DJ-1; GATD2; HEL-S-67p Entrez GeneID:11315 Swissprot:Q99497 clone:2B1G12 WB Predicted band size:19.8kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human PARK7 (AA: 1-189) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000