HTR3A抗体;HTR3A Polyclonal Antib

Description The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. References 1.PLoS One. 2015 Dec 23;10(12):e0145269. 2.Iran J Allergy Asthma Immunol. 2014 Feb;13(1):33-9. Specification Aliases:HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R Entrez GeneID:3359 Swissprot:P46098 clone:3B11C10 WB Predicted band size:55.3kDa Host/Isotype:Mouse IgG2a Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human HTR3A (AA: extra 24-157) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 ICC:1/100 - 1/500 FCM:1/200 - 1/400 ELISA:1/10000