F5(Coagulation factor V heavy

Description This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. Specification Aliases:FVL; PCCF; THPH2; RPRGL1 Swissprot:P12259 Host/Isotype:Rabbit IgG Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse Immunogen:Synthetic peptide of human F5(Coagulation factor V heavy chain) Formulation:pH7.4 PBS, 0.05% NaN3, 40% Glycerol Application IHC:1/20-1/100 ELISA:1/2000-1/5000