TNFRSF11B抗体;TNFRSF11B Polyclon

Description The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. References 1. Am J Hypertens. 2009 Nov;22(11):1167-70. 2. Am J Hum Genet. 2009 Nov;85(5):628-42. Specification Aliases:OPG; TR1; OCIF; MGC29565; TNFRSF11B Entrez GeneID:4982 Swissprot:O00300 clone:5G2 WB Predicted band size:60kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human TNFRSF11B expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000