MYL2抗体;MYL2 Polyclonal Antibod

Description MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. References 1. DNA Seq. 2003 Oct;14(5):339-50. 2. Oncogene. 2002 Aug 29;21(38):5852-60. Specification Aliases:MLC2; CMH10; DKFZp779C0562 Entrez GeneID:4633 Swissprot:P10916 clone:7C9 WB Predicted band size:19kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of MYL2 expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application WB:1/500 - 1/2000 ELISA:1/10000