CBX2抗体;CBX2 Polyclonal Antibod

Description This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. References 1.Br J Cancer. 2014 Oct 14;111(8):1663-72. 2.Fertil Steril. 2013 Mar 1;99(3):819-826. Specification Aliases:M33; CDCA6; SRXY5 Entrez GeneID:84733 Swissprot:Q14781 clone:4D10B2 WB Predicted band size:56kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Mouse Immunogen:Purified recombinant fragment of human CBX2 (AA: 402-525) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 ELISA:1/10000