ALDOA抗体;ALDOA Polyclonal Antib

Description The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. References 1.Cancer Lett. 2016 Apr 28;374(1):127-35. 2.Oncol Rep. 2014 Nov;32(5):2031-7. Specification Aliases:ALDA; GSD12; HEL-S-87p Entrez GeneID:226 Swissprot:P04075 clone:1C5B2 WB Predicted band size:39.4kDa Host/Isotype:Mouse IgG2a Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Mouse Immunogen:Purified recombinant fragment of human ALDOA (AA: 9-145) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000