Zaprinast

分子式：C13H13N5O2；分子量：271.3；外观：Pale Pink to Pink Solid；溶解性：DMSO (Slightly), Methanol (Slightly)；别名：3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one; 8-Aza-2-(2-propoxyphenyl)-6-purinone; M&B 22,948；熔点：229-233°C (dec.)；应用：A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of atrial natriuretic factor (ANF) through the activation of PKG (cGMP dependent protein kinase), such inhibitors may display vasodilating, relaxant, and diuretic effects. These compounds may prove useful in treating hypertension and congestive heart failure.；类别：Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,；储存温度：-20˚C Freezer。