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- 英文名:
Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]
- 库存:
1
- 供应商:
上海甄准
- CAS号:
1337482-15-1
- 规格:
5mg
分子式:C22H29FN3O9P;分子量:529.45;别名:(2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate;应用:Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate] is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.;类别:Heterocycles, Impurities, Nucleotides, Bases
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Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate],C22H29FN3O9P
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