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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
QuantiSir Specific Gene Knockdown Quantification Kit For Signal Transduction-GSK3-α (96 assays)
- 供应商:
上海西宝
- 规格:
96次分析
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文献和实验eliminate the guesswork--and the tedious labwork--associated with siRNA design and testing. Applied Biosystems' gene-specific, ready-to-run TaqMan® Gene Expression Assays provide you with a fast, simple way to measure the efficacy of mRNA knockdown
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
is specific to cellular activation by growth factors and nutrients. Wnt inhibition of GSK3 does not involve phosphorylation of these residues on GSK3 and therefore it cannotbe measured using this modification. Currently, the simplest way to assess Wnt
of the serine/threonine kinaseAkt, which will phosphorylate GSK-3 at specific serine residues(Ser21 in GSK-3a and Ser9 in GSK-3b), leading to the inactivationof GSK-3 kinase activity (10) . However, this phosphorylationand inactivation of GSK-3 by Akt
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