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- 详细信息
- 文献和实验
- 技术资料
- 库存:
100 µl
- 供应商:
西宝生物
- 英文名:
MICROTUBULE ASSOCIATED PROTEIN 2MONOCLONAL ANTIBODY
- 保存条件:
-20 C
- 规格:
IMMUNOBIOLOGICALS
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文献和实验Screening for Inhibitors of Microtubule-Associated Motor Proteins
The mitotic spindle is an important target for cancer chemotherapy. The main protein target for drugs in clinical use is tubulin, the building block of microtubules. In recent years, other proteins of the mitotic spindle have been identified
-associated protein 2 [MAP2] (2 ). The assay depends upon the observation that release of small peptides carrying only one fluorescent label, by digestion of a protein labeled with many fluorescent groups, is accompanied by a significant increase
为细胞中的直径约为 24毫微米的中空的微管,由分子量约 5.5万的球形微管蛋白所组成,大约 13个微管蛋白为一个单位集合成一根圆筒形的微管,还含有分子量 5.5万— 30万的各种微管结合蛋白质( mic- rotubular associated protein),与微管的联合有关。关于微管与细胞运动的关系,一般认为,在纤毛和鞭毛上,其周缘存在呈“ 8”字形断面的 9组双线( doublet)微管,和位于中心部的两根单线( si-nglet)微管,单宁蛋白( dynein)在周缘
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