CNTF, Human, Recombinant

CNTF, Human, Recombinant

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  • ¥1480 - 25680
  • Procell
  • PCK117
  • 武汉
  • 2025年07月09日
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    • 详细信息
    • 技术资料
    • 供应商

      武汉益普生物科技有限公司

    • 英文名

      CNTF, Human, Recombinant

    • 规格

      10μg/50ug/500ug/1mg

    规格:10μg产品价格:¥1480.0
    规格:50ug产品价格:¥3980.0
    规格:500ug产品价格:¥17480.0
    规格:1mg产品价格:¥25680.0

    产品信息

    别名Ciliary Neurotrophic Factor; CNTF
    物种Human
    表达宿主E.coli
    序列信息Ala2-Met200
    检索号P26441
    分子量22.93 kDa
    表观分子量25 kDa

     

    产品特性

    纯度>95% as determined by reducing SDS-PAGE.
    内毒素<1.0 EU per µg as determined by LAL test.
    保存Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    背景介绍

    Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their Protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle Cytokines share gp130 as a signal transducing subunit in their Receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-Derived endothelial cell Growth Factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.

    CNTF, Human, Recombinant

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