Flt-3L/ Flt3LG (C-6His), Human, Recombinant

Flt-3L/ Flt3LG (C-6His), Human

, Recombinant
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  • ¥1380 - 25680
  • Procell
  • PCK090
  • 武汉
  • 2025年07月16日
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    • 详细信息
    • 技术资料
    • 供应商

      武汉益普生物科技有限公司

    • 英文名

      Flt-3L/ Flt3LG (C-6His), Human, Recombinant

    • 规格

      10μg/50ug/500ug/1mg

    规格:10μg产品价格:¥1380.0
    规格:50ug产品价格:¥3680.0
    规格:500ug产品价格:¥17480.0
    规格:1mg产品价格:¥25680.0

    产品信息

    别名Fms-related Tyrosine Kinase 3 Ligand; Flt3 Ligand; Flt3L; SL Cytokine; FLT3LG
    物种Human
    表达宿主Human Cells
    序列信息Thr27-Pro184
    检索号P49771
    分子量19 kDa
    表观分子量24-32 kDa
    标签C-6His
    生物活性Immobilized Human FLT3LG (C-6His) 5 μg/ml (100 μl/well) can bind Human FLT3 (C-Fc). The EC50 of Human FLT3 (C-Fc) is not higher than 10 ng/ml.

     

    产品特性

    纯度>95% as determined by reducing SDS-PAGE.
    内毒素<1.0 EU per µg as determined by LAL test.
    保存Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    背景介绍

    Fms-Related Tyrosine Kinase 3 Ligand (FLT3LG) is a hematopoietic four helical bundle Cytokine. Mature human Flt-3 Ligand consists of a extracellular domain (ECD) with a Cytokine-like domain and a juxtamembrane tether region, a transmembrane segment, and a cytoplasmic tail. Human and mouse Flt-3 Ligand show cross-species activity. Flt-3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts.It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergy with other Growth Factors, Flt3 Ligand stimulates the proliferation and differentiation of various blood cell progenitors by activiation of Flt 3 Receptor.

    Flt-3L/ Flt3LG (C-6His), Human

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    ¥1380 - 25680