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TNF-β/ TNFB/ TNFSF1, Human, Re

combinant
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  • ¥1480 - 19980
  • Procell
  • PCK053
  • 武汉
  • 2025年07月07日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      武汉益普生物科技有限公司

    • 英文名

      TNF-β/ TNFB/ TNFSF1, Human, Recombinant

    • 规格

      10μg/50ug/500ug/1mg

    规格:10μg产品价格:¥1480.0
    规格:50ug产品价格:¥3980.0
    规格:500ug产品价格:¥13380.0
    规格:1mg产品价格:¥19980.0

    产品信息

    别名Lymphotoxin-Alpha; LT-Alpha; TNF-Beta; Tumor Necrosis Factor Ligand Superfamily Member 1; LTA; TNFB; TNFSF1
    物种Human
    表达宿主E.coli
    序列信息Leu35-Leu205
    检索号P01374
    分子量18.8 kDa
    表观分子量15 kDa
    生物活性Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 20-80 pg/ml.

     

    产品特性

    纯度>95% as determined by reducing SDS-PAGE.
    内毒素<1.0 EU per µg as determined by LAL test.
    保存Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    背景介绍

    Tumor Necrosis Factor β (TNF-β) is a secreted Protein belonging to the tumor necrosis factor family. TNF-β binds to TNFRSF1A/ TNFR1, TNFRSF1B/ TNFBR and TNFRSF14/ HVEM in homotrimeric form, binds to TNFRSF3/ LTBR in heterotrimeric form with LTB. TNF-β forms heterotrimers with lymphotoxin-beta, which anchors TNF-β to the cell surface. TNF-β mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF-β is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.

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