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Recombinant Human Latent GDF-8

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  • ¥2400 - 7200
  • 近岸蛋白(Novoprotein)
  • C43S
  • 国产
  • 2025年11月10日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现货

    • 英文名

      Recombinant Human Latent GDF-8

    • CAS号

    • 保质期

      6个月

    • 供应商

      上海经科化学科技有限公司

    • 保存条件

      -70℃

    • 规格

      10ug/50ug

    规格:10ug产品价格:¥2400.0
    规格:50ug产品价格:¥7200.0
    产品描述
    Recombinant Human Latent GDF-8 is produced by our Mammalian expression system and the target gene encoding Asn24-Ser375 is expressed with a 8His, Flag tag at C-terminus.
     
    蛋白编号
    O14793
     
    产品别称
    Growth/differentiation factor 8; MSTN; GDF-8; Myostatin; GDF8
     
    分子量
    29.8&12.4 KDa
     
    表观分子量
    (13-15)&(36-48) KDa, reducing conditions
     
    剂型描述
    Supplied as a 0.2 μm filtered solution of PBS, 5% Trehalose, 5% Mannitol, 0.02% Tween80, pH7.4.
     
    内毒素
    <1EU/μg as determined by LAL test.
     
    纯度-SDS-PAGE
    产品细节图片1
    Greater than 95% as determined by reducing SDS-PAGE.
     
    生物活性-BLI
    产品细节图片2Loaded Recombinant anti-Latent GDF8 mAb on Pro-A Biosensor, can bind Recombinant Human Latent GDF-8 (N-8His-Flag) (Cat#C43S) with an affinity constant of 11 nM as determined in BLI assay. (Regularly tested)
     
    运输条件
    • The product is shipped on dry ice/polar packs.
    • Upon receipt, store it immediately at the temperature listed below.
     
    保存条件
    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.
     
    产品背景
    Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.

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    图标文献和实验
    该产品被引用文献

    Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.

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    文献支持
    Recombinant Human Latent GDF-8
    ¥2400 - 7200