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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Fusion protein of Human IL1RN
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P18510
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,IHC;ELISA:1:1000-1:2000,IHC:1:25-1:100
- 浓度:
>95%,Antigen affinity purification
- 靶点:
IL1RN
- 抗体英文名:
IL1RN Antibody
- 抗体名:
Type II interleukin 1 receptor antagonist antibody
- 规格:
100μl/50μl
| 规格: | 100μl | 产品价格: | ¥1980.0 |
|---|---|---|---|
| 规格: | 50μl | 产品价格: | ¥1100.0 |
保存缓冲液
-20℃, pH7.4 PBS, 0.05% NaN3, 40% Glycerol功能
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验DL-IL1z-HuOverview:Other names:IL1F7; IL37; FIL1; FIL1(ZETA); FIL1Z; IL-1F7; IL-1 H4; IL-1RP1; IL1 H4; IL1RP1; Interleukin 37; Interleukin-1-Related Protein; Interleukin 1 Family, Member 7Function:Suppressor of innate inflammatory and immune
Reveals Systemic Dissemination of Herpes Simplex Virus Type 1 in the Absence of Interferon Receptors. JOURNAL OF VIROLOGY 77(20):11082-11093, 2003 小鼠干扰素受体缺失情况会直接影响1型单纯疱疹病毒(HSV-1)的感染模式。本文观察了荧光素酶基因标记的HSV对小鼠的感染过程,揭示只有在I型和II型干扰素受体均缺失的情况下,HSV-1的感染才是致命的。仅仅I型
inhibitory receptor,KIRs),若与自身靶细胞上的MHC I类分子及自身多肽形成的复合物结合时,则关闭NK细胞的杀伤作用。而外来细胞上的MHC I类分子不能被NK细胞抑制性受体所识别,不能抑制NK细胞对其杀伤。人类NK细胞表面分子P58、HP3E4和NKB1具有KIR特征。NK细胞释放的杀伤介质穿孔素、NK细胞毒因子(NKCF)、TNF等使靶细胞溶解破裂。NK细胞还可以通过人抗肿瘤抗体IgG1和IgG3作为桥梁,其Fab端特异性识别肿瘤,Fc段与NK细胞FcRgⅢa结合,产生抗体依赖的细胞
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