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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Fusion protein of Human CRELD2
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q6UXH1
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,WB,IHC;ELISA:1:2000-1:5000,WB:1:500-1:2000,IHC:1:50-1:200
- 浓度:
>95%,Antigen affinity purification
- 靶点:
CRELD2
- 抗体英文名:
CRELD2 Antibody
- 抗体名:
CRELD2 antibody;UNQ185/PRO211Protein disulfide isomerase CRELD2 antibody;EC 5.3.4.1 antibody;Cysteine-rich with EGF-like domain protein 2 antibody
- 规格:
100μl/50μl
| 规格: | 100μl | 产品价格: | ¥1980.0 |
|---|---|---|---|
| 规格: | 50μl | 产品价格: | ¥1100.0 |
保存缓冲液
-20℃, pH7.4 PBS, 0.05% NaN3, 40% Glycerol功能
The epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion and neural and vertebrate development. CRELD2 (cysteine-rich with EGF-like domains 2) is a 353 amino acid protein that is ubiquitously expressed and contains two FU domains and two EGF-like domains. Localized to the endoplasmic reticulum and secreted into the cell, CRELD2 interacts with AChR 4, possibly regulating its transport. Human CRELD2 shares 69% amino acid identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of CRELD2 exist due to alternative splicing events. The gene encoding CRELD2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验的Western Blotting一样好,但是时间可以大大缩短,包含transfer、blocking、washing、2nd antibody需要2天,数据分析约需要2-3天,整个过程大约1周的时间,比传统Western Blotting快48倍。这种新的技术,可以用极少量的样品和抗体分析大量数目不同蛋白的变化,极适合研究干细胞、癌细胞、组织发育等过程中信号传导路径(signaling transduction pathway)的变化。 研究人员将MWA技术与传统的Western Blot
的Western Blotting一样好,但是时间可以大大缩短,包含transfer、blocking、washing、2nd antibody需要2天,数据分析约需要2-3天,整个过程大约1周的时间,比传统Western Blotting快48倍。这种新的技术,可以用极少量的样品和抗体分析大量数目不同蛋白的变化,极适合研究干细胞、癌细胞、组织发育等过程中信号传导路径(signaling transduction pathway)的变化。 研究人员将MWA技术与传统的Western Blot
determinant,抗原决定簇 ADA:adenosine deaminase,腺苷脱氨酶 ADCC:antibody-dependent cell-mediated cytotoxicity)抗体依赖细胞介导性细胞毒性 Adjuvant therapy:辅助治疗 AEL:acute erythrocytic leukemia,急性红白血病 AEoL:acute eosinophilic leukemia,急性嗜酸粒细胞白血病 aGVHD:acute graft versus host
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