- ￥2024
- CUSABIO
- CN
- CSB-PA219426
- 2025年07月12日
- ELISA,WB;WB:1:500-1:3000
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthesized peptide derived from internal of Human MARK.
- 亚型：
/
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
/
- 适应物种：
Human,Mouse,Rat
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q9P0L2
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA,WB;WB:1:500-1:3000
- 浓度：
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点：
MARK1
- 抗体英文名：
MARK1 Antibody
- 抗体名：
/
- 规格：
100μl
保存缓冲液
/功能
Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).Lizcano J.M., EMBO J. 23:833-843(2004).
Nagase T., DNA Res. 7:143-150(2000).
Gregory S.G., Nature 441:315-321(2006).
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文献和实验该产品被引用文献
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文献支持
MARK1抗体MARK1兔多抗抗体/抗体MARK1 Antibody抗体
￥2024
