EIF4EBP1抗体EIF4EBP1一抗抗体Phosphor
ylated heat- and acid-stable protein regulated by insulin 1 antibody抗体EIF4EBP1 Antibody抗体- ￥2640
- CUSABIO
- CN
- CSB-PA007561KA01HU
- 2025年07月14日
- ELISA,WB,IHC;WB:1:500-1:2000,IHC:1:50-1:200
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein of Human EIF4EBP1
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
/
- 标记物：
/
- 适应物种：
Human,Mouse,Rat
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q13541
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA,WB,IHC;WB:1:500-1:2000,IHC:1:50-1:200
- 浓度：
>95%,Affinity purification
- 靶点：
EIF4EBP1
- 抗体英文名：
EIF4EBP1 Antibody
- 抗体名：
Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody
- 规格：
100μl
保存缓冲液
Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.功能
Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity. Multiple 4E-BP1 residues are phosphorylated in vivo. While phosphorylation by FRAP/mTOR at Thr37 and Thr46 does not prevent the binding of 4E-BP1 to eIF4E, it is thought to prime 4E-BP1 for subsequent phosphorylation at Ser65 and Thr70.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Strategies to Optimize Protein Expression in E. coli
, R.B., and Waugh, D.S. 2001. Single amino acid substitutions on the surface of Escherichia coli maltose‐binding protein can have a profound impact on the solubility of fusion proteins. Protein Sci. 10:622‐630.
ANALYSIS OF PROTEINS BY IMMUNOPRECIPITATION
for studying conceptus interferons in the cow. J. Reprod. Immunol. 18 , 205-223. Edwards, J.L., Ealy, A.D., Monterroso, V.H., and Hansen, P.J. (1997) Ontogeny of temperature-regulated heat shock protein 70 synthesis in preimplantation bovine embryos. Mol
.E.B., Seawright, A.A., Prakash,A.S., 1998. Dehydromonocrotaline generates sequence-selective N-7 guanine alkylation and heat and alkali stable multiple fragment DNA crosslinks. Nucleic Acids Res. 26, 5441–5447. Raingeaud, J., Grupta, S., Rogers, J.S
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