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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Integrin beta-2 protein (37-201AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P05107
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
- 浓度:
>95%,Protein G purified
- 靶点:
ITGB2
- 抗体英文名:
ITGB2 Antibody
- 抗体名:
ITGB2;CD18;MFI7;Integrin beta-2;Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;Complement receptor C3 subunit beta;CD antigen CD18
- 规格:
100μg/50μg/20μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
| 规格: | 20μg | 产品价格: | ¥440.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation (PubMed:18587400). Integrin alpha-L/beta-2 in assosiation with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590).风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验关键词(如:CD56),并在后方的应用栏选择相应的应用技术,点击搜索即可。界面清晰明了,缺点是收录的抗体供应商相对较少(约85家)。 05 Antibodyresource 网址:https://www.antibodyresource.com/ Antibodyresource(www.antibodyresource.com)上,可以非常简便地查找抗体和ELISA试剂。 06 Antibody Validation Database 网址:http://compbio.med.harvard
抗原抗体反应 antigen-antibody reaction
基于抗原同抗体的特异性结合产生的现象总称。实际的结合取决于抗原的抗原决定簇和抗体的抗原结合部位(结合簇)(antigen combining site)之间的特殊结合。在生物体内发生的抗原抗体反应(免疫、过敏反应、溶血等)多数也可在试管内再现,利用这一点发展了抗原或抗体的定性及定量的试验方法。像酶、毒素、病毒之类具有生物学活性的抗原,一与抗体(中和抗体)结合,其活性便消失或减弱(中和反应, neutralizing reaction)。带有可溶性的复数抗原决定簇的抗原分子,与抗体互相
(杨希峰),Yang CY(杨春瑛) et al. Generation and characterization of monoclonal antibody against HIT3a (抗CD3单克隆抗体HIT3a的制备和特异性鉴定), Acta Academiae Medicinae Sinicae (中国医学科学院学报),1993, 15:157-162.[6] Xiong D S(熊冬生),Yang C Z(杨纯正),Shao X F(邵晓枫)et al. Generation
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