- ￥440 - 1320
- CUSABIO
- CN
- CSB-PA892346ESR1HU
- 2025年07月16日
- ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human E3 ubiquitin-protein ligase CBL-C protein (245-474AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q9ULV8
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- 浓度：
>95%,Antigen Affinity Purified
- 靶点：
CBLC
- 抗体英文名：
CBLC Antibody
- 抗体名：
Signal transduction protein CBL-C antibody
- 规格：
100μl/50μl/20μl
| 规格： | 100μl | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μl | 产品价格： | ￥880.0 |
| 规格： | 20μl | 产品价格： | ￥440.0 |
保存缓冲液
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.功能
Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Functionally coupled with the E2 ubiquitin-protein ligases UB2D1, UB2D2 and UB2D3. Regulator of EGFR mediated signal transduction; upon EGF activation, ubiquitinates EGFR. Isoform 1, but not isoform 2, inhibits EGF stimulated MAPK1 activation. Promotes ubiquitination of SRC phosphorylated at \'Tyr-419\'. In collaboration with CD2AP may act as regulatory checkpoint for Ret signaling by modulating the rate of RET degradation after ligand activation; CD2AP converts it from an inhibitor to a promoter of RET degradation; the function limits the potency of GDNF on neuronal survival.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验抗核抗体(anti-nucleic antibody，ANA)检测
抗核抗体(anti-nucleic antibody，ANA)是以真核细胞的核成分为靶抗原的自身抗体的总称。细胞核内含有许多不同成分如核蛋白、核糖核蛋白(ribonucleo protein，RNP)、脱氧核糖核酸(DNA)等。 在某些因素，如细菌、病毒、药物等作用下，可改变细胞核某些成分的性质，激发机体免疫系统产生许多抗不同核成分的抗体。
双特异抗体(Bispecific antibody)的简介和制作方法
contain two identical antigen-binding arms and a constant fragment, (Fc)g. The Fc part enables the antibody to function as an adaptor protein, linking antibody-bound cells to immune cells bearing Fcg receptors. Because there are different Fcg receptors
-phosphoserine的抗体。 摘抄： Anti-Phosphothreonine (MAb) - CryptateThe anti-phosphothreonine antibody is a monoclonal antibody (clone 42H4) produced at Cell Signaling Technology (reference 9386). It recognizes phosphorylated threonine residues in a manner
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