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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Melanocyte-stimulating hormone receptor (MC1R)-VLPs
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
1mg/100μg/20μg
| 规格: | 1mg | 产品价格: | ¥40068.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | ¥7560.0 |
| 规格: | 20μg | 产品价格: | ¥3780.0 |
纯度:
The purity information is not available for VLPs proteins.基因名:
MC1RUniprot No.:
Q01726别名:
MSH-R;Melanocortin receptor 1;MC1-R种属:
Homo sapiens (Human)蛋白长度:
Full Length来源:
Mammalian cell分子量:
36.1 kDa表达区域:
1-317aa氨基酸序列:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW蛋白标签:
C-terminal 10xHis-tagged(This tag can be tested only under denaturing conditions)产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4.货期:
18-28 business days注意事项:
The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex.Repeated freezing and thawing is not recommended.Store the protein at -20℃/-80℃ upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).功能:
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.内毒素:
/SDS-PAGE:
CSB-MP086369HU is detected by Mouse anti-6*His monoclonal antibody.LC-MS Image Description/Western Blot:
/Product types:
MP-VLP Transmembrane Protein & Developed ProteinBiological_Activity:
/Research Areas:
Signal TransductionReconstitution:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80℃. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.Reference:
/Function:
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文献和实验Acute myeloid leukemia (AML) has an annual incidence of 2.4 cases per 100,000 persons and is the most common form of acute leukemia in adults (1 , 2 ). AML is a model for drug-resistant human cancers, and current therapies for AML possess
Molecular Analysis of Human Resistance to Thyroid Hormone Syndrome
Resistance to thyroid hormone (RTH) syndrome is an inherited human endocrine disease, which is manifested as a failure to respond properly to elevated circulating thyroid hormone (1 -4 ). RTH syndrome behaves as an autosomal dominant trait
until such sequences appear in the rapidly growing sequence databases from rodent and human genome projects. This method has been used to identify a novel member of the steroid receptor superfamily (1 –3 ) and may ultimately result in the identification
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