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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG1
- 形态:
Liquid
- 保存条件:
at-20℃
- 适应物种:
Rabies lyssavirus
- 库存:
99
- 宿主:
Human
- 应用范围:
FCM,Neutralization
- 浓度:
见说明
- 抗体英文名:
Anti-Rabies lyssavirus G/Glycoprotein Monoclonal antibody (RVC111)
- 规格:
50-100ug
抗Rabies lyssavirus G/Glycoprotein单克隆抗体(克隆号RVC111)上海圻明生物优势供应欢迎咨询。配对抗体小课堂:
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.

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文献和实验Lyssaviruses: Special Emphasis on Rabies Virus and Other Members of the Lyssavirus Genus
Rabies is routinely diagnosed based on the clinical description and history of exposure in a rabies-endemic country. A negative diagnostic test for rabies virus or a related lyssavirus does not exclude the clinical diagnosis. Diagnostic tests
Lyssaviruses: Special Emphasis on Rabies Virus
Lyssavirus infection, better known as rabies, in animals or in humans, is characterized by a clinical picture of viral encephalitis. According to the WHO estimations, it is responsible for more than 50,000 human deaths each year
狂犬病病毒(rabies virus)为弹状病毒科 (rhabdoviridae)狂犬病毒属 (lyssavirus) 中血清/基因1型病毒,而2~6型称“狂犬病相关病毒”,目前仅在非洲和欧洲发现。狂犬病病毒在野生动物(狼、狐狸、鼬鼠、蝙蝠等)及家养动物(狗、猫、牛等)与人之间构成狂犬病的传播环节。人主要被病兽或带毒动物咬伤后感染。一旦受染,如不及时采取有效防治措施,可导致严重的中枢神经系统急性传染病,病死率高,在亚非拉发展中国家中每年有数万人死于狂犬病。 病毒外形呈弹状(60~
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