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AJE 润色服务限时 8 折起,权威机构信任 15+ 年Cytoscape 教程来了!快速实现顶刊同款通路网络图五大应用案例:Mustang Q 膜层析应用全解析1 个小工具,一次性搞定流程图、质粒图谱和信号通路图- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG2a, kappa
- 形态:
Liquid
- 保存条件:
at-20℃
- 库存:
99
- 宿主:
Mouse
- 应用范围:
IHC,WB
- 浓度:
见说明
- 抗体英文名:
Anti-LRRK2/Dardarin Monoclonal antibody (N241A/34)
- 规格:
50-100ug
小鼠抗LRRK2/Dardarin单克隆抗体(克隆号N241A/34)上海圻明生物优势供应欢迎咨询。配对抗体小课堂:
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.

小鼠抗LRRK2/Dardarin单克隆抗体(克隆号N241A/34)更多优势产品欢迎新老客户选购。
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文献和实验国自然/高分文章利器!CRISPR文库筛选保姆级指南:从Cas9递送到表型选择一文打通!
研究机构:南开大学 研究人员利用靶向23,439个小鼠基因的全基因组CRISPRa文库,筛选了在LPS刺激下促进B16黑色素瘤细胞转化为MDSC样肿瘤细胞(MLTCs)的关键调控因子。该筛选鉴定出RNA结合蛋白Rbfox3为关键驱动因子。Rbfox3形成相分离的核内液滴,在转录水平抑制Ass1基因的表达,从而发挥免疫抑制功能。天然产物藏红花素可破坏Rbfox3的相分离,抑制MLTC的产生,并增强抗PD-1疗法的疗效。 Adv Sci (Weinh). 2025 Feb;12
,Karlsruhe,Germany) 。 ( 3 ) GenePixPro 4.0 软件。 1. 在 FAST 点样基片上的单克隆抗体筛选 ( 1 ) TBS + Tween-20 ( TBST ) :10 mmol/L Tris-HCl,pH 7.5,150 mmol/L NaCl,0.1% ( V/V ) Tween-20。 ( 2 ) 封闭液:2% 牛血清蛋白(BSA ) ( Sigma,St. Louis,MO) 溶于 TBST 中。 ( 3 ) 小鼠抗 RGS
分子。 表1-2 CD分子的主要特征 CD 常用单克隆抗体或代号( ) 主要表达细胞 分子量(kDa)和结构 功能 CDla T6,Leu6 Thy,DC,LHC gp49 TCRγδ的配体? CDlb WM-25,4A76,NUT2 Thy,LHC gp45 TCRγδ的配体? CDlc L161,M241,7C6 Thy,DC,Bsub gp43 TCRγδ的配体? CD2 9.6,T11,Leu5; (LFA-2,SRBC-R) T,NKsub. gp
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