- 询价
- KA&M BIO
- MAB4083
- 2025年10月14日
- IHC,WB
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG2a, kappa
- 形态：
Liquid
- 保存条件：
at-20℃
- 库存：
99
- 宿主：
Mouse
- 应用范围：
IHC,WB
- 浓度：
见说明
- 抗体英文名：
Anti-Neuronal acetylcholine receptor subunit beta4 Monoclonal antibody (N434/81)
- 规格：
50-100ug
小鼠抗Neuronal acetylcholine receptor subunit beta4单克隆抗体(克隆号N434/81)上海圻明生物优势供应欢迎咨询。配对抗体小课堂：
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.
小鼠抗Neuronal acetylcholine receptor subunit beta4单克隆抗体(克隆号N434/81)更多优势产品欢迎新老客户选购。
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文献和实验Identification of Mutations in the Kir6.2 Subunit of the KATP Channel
The beta-cell ATP-sensitive potassium channel is a key component of stimulus —secretion coupling in the pancreatic beta-cell. The channel consists of four subunits of the inwardly rectifying potassium channel Kir6.2 and four subunits
在小鼠和人类肥胖过程、胰岛素抵抗和肥胖相关的炎症过程的脂肪组织中上调 (3)。通过 coIP（免疫共沉淀）实验证明，ANGPTL2 和 CD146 存在直接相互作用。这种相互作用促进脂肪形成，脂质积累和脂肪炎症。图片来源：Advanced Science 4. 靶向 CD146 单克隆抗体 AA98 可预防肥胖和胰岛素抵抗。 探究抗 CD146 单克隆抗体 AA98 是否可以预防肥胖症及其相关并发症。作者使用 AA98 处理小鼠，结果显示 BAT 重量降低和脂滴减少。此外，AA98 治疗上调
[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
), transcript variant MB-COMT, mRNA 845 NM_002406 Homo sapiens mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT1), mRNA 893 NM_003752 Homo sapiens eukaryotic translation initiation factor 3, subunit 8, 110kDa (EIF3S8), mRNA
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