- 询价
- KA&M BIO
- MAB4003
- 2025年07月08日
- IHC,WB
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG2a, kappa
- 形态：
Liquid
- 保存条件：
at-20℃
- 库存：
99
- 宿主：
Mouse
- 应用范围：
IHC,WB
- 浓度：
见说明
- 抗体英文名：
Anti-Alpha-2A adrenergic receptor Monoclonal antibody (N379/52)
- 规格：
50-100ug
小鼠抗Alpha-2A adrenergic receptor单克隆抗体(克隆号N379/52)上海圻明生物优势供应欢迎咨询。配对抗体小课堂：
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.
小鼠抗Alpha-2A adrenergic receptor单克隆抗体(克隆号N379/52)更多优势产品欢迎新老客户选购。
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文献和实验Isolation of Adrenergic Receptor Genes
In order to isolate a single gene, phage or cosmid libraries can be screened by the conventional technique of hybridization as described by Sambrook et al. (1 ) using end-labeled oligonucleotide probes or gene-specific probes. The probes
Analyses of Adrenergic Receptor Sequences
with known adrenergic receptor sequences in order to verify the receptor and subtype, to submit the sequence to GenBank, and to analyze the predicted secondary structure of the receptor.
Targeted Disruption of Adrenergic Receptor Genes
. This approach has been particularly useful for studies on adrenergic receptor (AR) function, having been used to effect disruption of at least six of the nine known AR genes (1 –6 ). As presented here, the knockout strategy is essentially a synthesis
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